Phylogenetic analyses and taxonomic revisions were conducted on the scarabaeoid family Hybosoridae. Two new subfamilies of Hybosoridae are described, Liparochrinae and Pachyplectrinae. Phylogenetic analysis and a systematic revision of the New World subfamily Anaidinae are provided. The phylogenetic analyses of the family Hybosoridae (co-authored with David C. Hawks), based on molecular data from the 28S D2 and D3 regions rDNA and 18S rDNA, support the monophyly of Hybosoridae. Five clades (referred to as subfamilies) comprise the Hybosoridae: Anaidinae, Ceratocanthinae, Hybosorinae, Liparochrinae (new subfamily), and Pachyplectrinae (new subfamily). As a result, the following family-group names have new status: Anaidinae (previously considered a tribe) and Ceratocanthinae (previously considered a family). Phylogenetic analyses of the subfamily Anaidinae, based on 117 adult morphological characters, support the monophyly of the subfamily, which now includes six genera: Anaides Westwood, Callosides Howden, Chaetodus Westwood, Cryptogenius Westwood, Hybochaetodus Arrow, and Totoia Ocampo. Descriptions of all subfamilies of Hybosoridae are provided. Keys to genera and species of Anaidinae, and synopses of all genera are provided. Two genera of Anaidinae are revised: Anaides and Chaetodus. The genus Anaides now includes 13 species, eight of which are new. The genus Chaetodus now includes two subgenera and 33 species, 19 of which are new. A new species in the genus Totoia Ocampo is described bringing the total number of species in this genus to three. A catalog of the world Hybosoridae species is provided (co-authored with Alberto Ballerio).